Related Experiment Video
Updated: Apr 26, 2026
03:25
Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
Published on: June 16, 2022
1.1K
[Organ and function preservation in urethral cancer]
S Tritschler1, K Lellig, A Roosen
1Urologische Klinik und Poliklinik, Klinikum Großhadern, Ludwig-Maximilians-Universität, München, Marchioninistraße 15, 81377, München, Deutschland, Stefan.Tritschler@med.uni-muenchen.de.
Der Urologe. Ausg. A
|August 13, 2014
Summary
Primary urethral carcinomas are rare cancers affecting both sexes. Treatment varies from surgical resection for localized disease to radical surgery or chemotherapy for advanced cases, with survival rates of 75% (1-year) and 54% (5-year).
Area of Science:
- Urology
- Oncology
Context:
- Primary urethral carcinomas are rare neoplasms affecting both male and female patients.
- Histological variants include urothelial tumors, squamous cell carcinomas, and adenocarcinomas.
- Prognosis is influenced by clinical factors, with 1- and 5-year cancer-free survival rates of 75% and 54%, respectively.
Purpose:
- To outline the histological patterns, clinical prognosis, and therapeutic strategies for primary urethral carcinomas.
Summary:
- Localized tumors are treated with surgical resection, potentially organ-preserving if complete resection is confirmed by frozen sections.
- Management may necessitate perineal urethrostomy in men or carries a risk of urinary incontinence in women if distal urethra resection exceeds 2 cm.
- Locally advanced or proximal urethral tumors require radical urethrectomy with urinary diversion, and neoadjuvant (radio)chemotherapy is an option.
Impact:
- Provides essential information for clinicians managing rare urethral cancers.
- Highlights the importance of surgical technique and histological assessment for patient outcomes.
- Informs treatment decisions, balancing oncological control with functional preservation and quality of life.
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