Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nucleus limitans thalami--comparative anatomical study.

J Moryś, J Dziewiatkowski, M Bobiński

    Acta Neurobiologiae Experimentalis
    |January 1, 1989
    PubMed
    Summary

    The nucleus limitans thalami, crucial for pain perception, shows evolutionary development across species. This pain pathway structure is phylogenetically recent, with increasing complexity observed from lower mammals to humans.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    How to write an umbrella review? A step-by-step tutorial with tips and tricks.

    Folia morphologica·2022
    Same author

    Neuroradiology diagnostic errors at a tertiary academic centre: effect of participation in tumour boards and physician experience.

    Clinical radiology·2022
    Same author

    Neuroglia - development and role in physiological and pathophysiological processes.

    Folia morphologica·2021
    Same author

    Can the kisspeptin help us in the understanding of pathology of some neurodegenerative brain diseases?

    Folia morphologica·2021
    Same author

    Role of brain-derived neurotrophic factor in shaping the behavioural response to environmental stressors.

    Folia morphologica·2021
    Same author

    Added value in stroke imaging: accuracy and utility of additional coronal diffusion-weighted imaging.

    Clinical radiology·2021

    Area of Science:

    • Neuroscience
    • Comparative Anatomy
    • Evolutionary Biology

    Background:

    • The nucleus limitans thalami is a key component of the brain's nociceptive (pain perception) system.
    • Understanding its structure and evolution provides insights into the development of pain processing pathways.
    • Previous research has not fully elucidated the phylogenetic trajectory of this structure.

    Purpose of the Study:

    • To investigate the cyto- and myeloarchitectonics and acetylcholinesterase activity of the nucleus limitans thalami.
    • To compare the structure of the nucleus limitans thalami across a range of mammalian species, including insectivores, rodents, lagomorphs, carnivores, primates, and humans.
    • To determine the phylogenetic age and evolutionary development of the nucleus limitans thalami.

    Main Methods:

    • Comparative cytoarchitectonic analysis of the nucleus limitans thalami.
    • Myeloarchitectonic mapping to delineate neural pathways.
    • Histochemical staining for acetylcholinesterase activity.
    • Species studied: Insectivora (Sorex araneus, Erinaceus europaeus, Talpa europaeus), rat, rabbit, cat, monkey, and human.

    Main Results:

    • The nucleus limitans thalami appears to be a phylogenetically recent structure.
    • In insectivores and rats, distinct neuronal groups resembling the nucleus limitans thalami were not readily identified.
    • In rabbits and cats, the nucleus limitans thalami consists of a few layers of elongated cells.
    • In macaques and humans, it is a more complex structure with diverse neuron types arranged in multiple layers.

    Conclusions:

    • The nucleus limitans thalami exhibits significant evolutionary changes in complexity across mammalian lineages.
    • Its development correlates with phylogenetic advancement, suggesting a more refined role in nociception in higher mammals.
    • Further research into the functional implications of these structural differences is warranted.

    Related Experiment Videos