[Application of process engineering to remove lignocellulose fermentation inhibitors]

Area of Science:

• Biotechnology
• Biochemical Engineering
• Sustainable Chemistry

Background:

• Fermentation inhibitors pose significant challenges in lignocellulose bio-refinery processes.
• Effective inhibitor management is crucial for efficient lignocellulose bioconversion.

Purpose of the Study:

• To review the sources, types, and removal strategies of fermentation inhibitors.
• To introduce innovative approaches for mitigating inhibitor toxicity in bio-refineries.

Main Methods:

• Comprehensive literature review of physical, chemical, and biological inhibitor removal techniques.
• Exploration of inhibitor-tolerant strain construction.
• Introduction of fractional conversion and fermentation promoter exploitation technology.

Main Results:

• Detailed overview of established and emerging inhibitor removal strategies.
• Presentation of a novel "fractional conversion" model to minimize inhibitor generation.
• Introduction of "fermentation promoter exploitation technology" for in situ detoxification.

Conclusions:

• Effective removal of fermentation inhibitors is key to advancing lignocellulose bio-refinery processes.
• Novel strategies like fractional conversion and in situ detoxification offer promising avenues for enhancing bioconversion efficiency.