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Churg strauss syndrome - a case report.
Mallikarjun Shetty1, Ramakrishna Janapati2, Krishnaprasad A3
1Assistant Professor, Department of Medicine, Nizam's Institute of Medical Sciences , Hyderabad, Telangana, India .
Journal of Clinical and Diagnostic Research : JCDR
|August 15, 2014
Summary
Churg Strauss syndrome, a rare condition, can manifest with asthma, sinusitis, and nerve damage. Early diagnosis is crucial for managing this eosinophilic vasculitis.
Area of Science:
- Internal Medicine
- Neurology
- Rheumatology
Background:
- Churg Strauss syndrome (CSS), also known as eosinophilic granulomatosis with polyangiitis (EGPA), is a rare systemic vasculitis.
- It is characterized by asthma, eosinophilia, and systemic multi-organ involvement.
Observation:
- A 45-year-old male with a history of asthma and sinusitis presented with fever, cough, breathlessness, and neurological symptoms.
- Physical examination revealed wheezing and signs of peripheral neuropathy.
- Investigations showed eosinophilia, reversible airway obstruction, and mononeuritis multiplex.
Findings:
- Muscle biopsy indicated eosinophilic infiltration, while nerve biopsy showed vacuities.
- Two-dimensional echocardiography revealed regional wall motion abnormalities, and coronary angiography showed coronary artery narrowing.
- The constellation of symptoms and findings led to the diagnosis of Churg Strauss syndrome.
Implications:
- This case highlights the diverse clinical manifestations of Churg Strauss syndrome.
- It underscores the importance of considering CSS in patients with asthma, sinusitis, and neurological deficits.
- Prompt diagnosis and management are essential to prevent severe organ damage and improve patient outcomes.
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