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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
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Obstructive sleep apnea and central serous chorioretinopathy
Frank L Brodie1, Emily S Charlson, Tomas S Aleman
1Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania.
Retina (Philadelphia, Pa.)
|August 16, 2014
Summary
This study found no significant association between obstructive sleep apnea (OSA) and central serous chorioretinopathy (CSCR). Our findings suggest that matching for body mass index may explain the lack of association, differing from prior research.
Area of Science:
- Ophthalmology
- Sleep Medicine
- Retinal Diseases
Background:
- Central serous chorioretinopathy (CSCR) is a condition affecting vision.
- Obstructive sleep apnea (OSA) is a common sleep disorder.
- Previous studies suggested a potential link between CSCR and OSA.
Purpose of the Study:
- To investigate the association between obstructive sleep apnea (OSA) and central serous chorioretinopathy (CSCR).
Main Methods:
- Patients with CSCR were matched with controls based on age, gender, and BMI.
- The Berlin Questionnaire was used to assess OSA risk.
- Rates of OSA+ were compared between groups using logistic regression.
Main Results:
- Forty-eight CSCR patients and matched controls were analyzed.
- No statistically significant difference in OSA risk was found between CSCR patients (45.8%) and controls (43.8%).
- The odds ratio for OSA in CSCR patients was 1.08 (95% CI, 0.47-2.49; P = 1.00).
Conclusions:
- Patients with CSCR did not exhibit statistically significant higher rates of OSA risk compared to matched controls.
- This finding diverges from previous research suggesting a strong association.
- Matching for BMI, a known OSA risk factor, may explain the discrepancy in findings.
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