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Published on: December 9, 2025
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A quantitative evaluation method using processed optical images and analysis of age-dependent changes on nasolabial
Sue Im Jang1, Eun Joo Kim, Hyeokgon Park
1AMORE PACIFIC Corporation/R&D CENTER, Yongin-Si Gyeonggi-do, Korea.
Summary
A new quantitative method using optical imaging effectively evaluates nasolabial lines (NL) severity. This method correlates NL severity with decreased skin elasticity and aging, offering a more objective assessment than visual scoring.
Area of Science:
- Dermatology and aging research.
- Image analysis and quantitative morphology.
Background:
- Nasolabial lines (NL) are key aging features, typically assessed subjectively.
- Existing methods for wrinkle analysis are often morphological, lacking quantitative precision for NL.
Purpose of the Study:
- To develop and validate a quantitative method for assessing nasolabial line severity.
- To explore the relationship between NL severity, skin elasticity, and chronological age.
Main Methods:
- Utilized VISIA-CR® for facial imaging and PRIMOS® for 3D wrinkle depth measurement in 100 Korean women (20-60 years).
- Quantified NL using pixel area and angle from processed images, alongside visual scoring and Cutometer® for skin elasticity.
- Statistical analysis determined significance at P < 0.05.
Main Results:
- VISIA-CR® images clearly distinguished NL, showing age-dependent increases.
- Skin elasticity parameters (R2, R5, R7) decreased with age, with R7 showing a strong negative correlation (r=-0.756).
- NL severity parameters (pixel number, angle, Ra, visual score) correlated with decreased elasticity and were linked to NL area pixel count.
Conclusions:
- Nasolabial line severity is significantly associated with reduced dermal elasticity and increasing age.
- The developed quantitative method using optical image processing provides an objective measure for NL evaluation.
- This approach offers a more precise alternative to traditional visual scoring for nasolabial lines.
