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Chronic rhinosinusitis patients have decreased lung function.
Shin Kariya1, Mitsuhiro Okano, Takaya Higaki
1Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
International Forum of Allergy & Rhinology
|August 19, 2014
Summary
Patients with chronic rhinosinusitis (CRS) exhibit impaired pulmonary function, even without asthma. This suggests subclinical lower airway diseases may be present in CRS patients, highlighting the need for lung function assessment.
Area of Science:
- Respiratory Medicine
- Otolaryngology
- Pulmonology
Background:
- The link between upper and lower airway conditions is recognized.
- Pulmonary function in chronic rhinosinusitis (CRS) patients remains under-investigated.
Purpose of the Study:
- To evaluate pulmonary function in patients diagnosed with CRS.
- To explore correlations between lung function and clinical indicators in CRS.
Main Methods:
- Pulmonary function tests were conducted on 273 CRS patients and 100 controls.
- CRS patients were subgrouped based on asthma, allergies, and nasal polyposis.
- Associations with CT staging, blood eosinophils, and IgE levels were analyzed.
Main Results:
- CRS patients demonstrated significantly altered pulmonary function compared to controls.
- Latent obstructive changes were noted in CRS patients even without a concurrent asthma diagnosis.
- No significant correlations were found between pulmonary function and clinical parameters.
Conclusions:
- Chronic rhinosinusitis is associated with significant obstructive lung function changes, irrespective of asthma.
- Subclinical lower airway disease may be present in CRS patients.
- Clinicians should consider assessing lung function in individuals with CRS.