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Generation of Size-controlled Poly ethylene Glycol Diacrylate Droplets via Semi-3-Dimensional Flow Focusing Microfluidic Devices
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Three-dimensional flash flow microreactor for scale-up production of monodisperse PEG-PLGA nanoparticles
Kyoung-Ik Min1, Do Jin Im, Hyune-Jea Lee
1Center of Applied Microfluidic Chemistry (CAMC), Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, 790-784, Republic of Korea. dpkim@postech.ac.kr.
Abstract:
We present a pressure-tolerant 3D parallel polyimide (PI) film microreactor operating at up to ~160 bars with direct 3D flow focusing geometry for mass production of PEG-PLGA nanoparticles in a ~10(1) gram-scale (g h(-1)).
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