Related Experiment Video
Updated: Apr 25, 2026
Ye's Swing Technique for Small-incision Lenticule Extraction Surgery
Published on: June 27, 2025
Five-year results of refractive lenticule extraction
Marcus Blum1, Andrea Flach1, Kathleen S Kunert1
1From the Department of Ophthalmology (Blum, Flach, Kunert), HELIOS Klinikum Erfurt, Erfurt, and the Department of Ophthalmology (Sekundo), Phillips University of Marburg, Marburg, Germany.
Purpose:
To evaluate the 5-year results of femtosecond laser-assisted refractive lenticule extraction (ReLEx-FLEx) for the treatment of myopia and myopic astigmatism.
Setting:
Departments of Ophthalmology, Helios Klinikum Erfurt, Erfurt, and Phillips Universität Marburg, Marburg, Germany.
Design:
Prospective clinical trial.
Methods:
This was a follow-up of a prospective study that evaluated the first patients treated with refractive lenticule extraction, in which a flap and a refractive lenticule of intrastromal corneal tissue were simultaneously cut using a 200 kHz Visumax femtosecond laser system. Thereafter, the lenticule was manually removed and the flap repositioned. The main outcome measures were the uncorrected and corrected distance visual acuities, objective and manifest refractions, slitlamp examination findings, and side effects after 5 years.
Results:
Forty-one of 108 eyes in the original treatment group were available for a reexamination. Five years postoperatively, 100% of eyes were within ±1.00 diopter (D) of the intended correction and 73% were within ±0.50 D. By 5 years, no eye had lost 2 or more Snellen lines and 1 eye had lost 1 Snellen line. The mean regression was 0.07 D.
Conclusion:
Long-term data indicate that refractive lenticule extraction is an effective and safe procedure for the treatment of myopia and myopic astigmatism and has excellent stability.
Financial Disclosure:
No author has a financial or proprietary interest in any material or method mentioned.
