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Febrile seizures: etiology, prevalence, and geographical variation

Ali Delpisheh1, Yousef Veisani2, Kourosh Sayehmiri3

  • 1Prevention of Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran ; Department of Clinical Epidemiology, Ilam University of Medical Sciences, Ilam, Iran.

Iranian Journal of Child Neurology
|August 22, 2014
PubMed

Insights

Febrile seizures (FSs) are common in Iranian children, with nearly half of childhood convulsions linked to them. Upper respiratory infections are a significant cause of FSs.

Area of Science:

  • Pediatric Neurology
  • Epidemiology
  • Infectious Diseases

Background:

  • Febrile seizures (FSs) are the most frequent neurological condition in children.
  • Understanding FS epidemiology and risk factors in specific populations is crucial for public health.

Purpose of the Study:

  • To determine the epidemiological and clinical characteristics of febrile seizures in Iranian children.
  • To identify risk factors associated with FS in this pediatric group.

Main Methods:

  • A systematic review and meta-analysis of existing literature.
  • Prevalence and confidence intervals calculated using a random effects model.
  • Metaregression analysis employed to investigate heterogeneity.

Main Results:

  • The pooled prevalence of FS among childhood convulsions was 47.9%.
  • Recent upper respiratory infections (42.3%), gastroenteritis (21.5%), and otitis media (15.2%) were identified as common causes.
  • Sample size did not significantly impact heterogeneity in FS prevalence.

Conclusions:

  • Febrile seizures account for nearly half of all childhood convulsions in Iran.
  • Infections, particularly respiratory ones, are strongly associated with FS.
  • Further research into specific risk factors and prevention strategies is warranted.
Abstract

Keywords:
Febrile seizureIranMeta–analysisPediatrics

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