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Updated: Apr 25, 2026

Experimental Manipulation of Body Size to Estimate Morphological Scaling Relationships in Drosophila
Published on: October 1, 2011
Modeling biology spanning different scales: an open challenge
Filippo Castiglione1, Francesco Pappalardo2, Carlo Bianca3
1Institute for Applied Mathematics, National Research Council of Italy, Rome, Italy.
Abstract:
It is coming nowadays more clear that in order to obtain a unified description of the different mechanisms governing the behavior and causality relations among the various parts of a living system, the development of comprehensive computational and mathematical models at different space and time scales is required. This is one of the most formidable challenges of modern biology characterized by the availability of huge amount of high throughput measurements. In this paper we draw attention to the importance of multiscale modeling in the framework of studies of biological systems in general and of the immune system in particular.
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