Related Experiment Video
Updated: Apr 25, 2026

Ultrasonographic Evaluation of Breast Cancer-related Lymphedema
Published on: January 12, 2017
Clinical features of docetaxel chemotherapy-related lymphedema
Sae In Park1, Woo Hyun Jeon, Ho Joong Jeung
1Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine , Busan, Korea.
Abstract:
Lymphedema is a chronic, progressive, and multifactorial disease. The anticancer drug docetaxel (Taxotere) can lead to fluid retention, which is the main cause of peripheral edema of the extremities, pleural effusion, pericardial effusion, and ascites in patients undergoing chemotherapy. While there have been a few case reports documenting fluid retention-induced edema as a side effect of docetaxel, it is not yet clear whether docetaxel causes lymphedema directly. Here, we report cases of three patients who developed lymphedema after treatment with docetaxel.
Related Concept Videos
Cytotoxic Edema: Pathophysiology
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Lymphatic Vessels and Lymph Transport
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular...
Development of the Lymphatic System
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...

