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TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples

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Advances in arsenic biosensor development--a comprehensive review.

Hardeep Kaur¹, Rabindra Kumar¹, J Nagendra Babu¹

¹Centre for Environmental Science and Technology, Central University of Punjab, Bathinda, Punjab 151001, India.

Biosensors & Bioelectronics

|August 25, 2014

Summary

This summary is machine-generated.

This review highlights advancements in arsenic biosensors, focusing on recombinant cells, oligonucleotides, and proteins for detecting toxic arsenic. It explores futuristic techniques like aptamer technology for improved arsenic monitoring in environmental and food samples.

Keywords:

Aptamer Arsenic toxicity Biosensor Recombinant whole cell Reporter proteins ars Operon

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Area of Science:

Analytical Chemistry
Biotechnology
Environmental Science

Background:

Biosensors offer sensitive, portable, and easy monitoring of analytes.
Arsenic (As) contamination is a significant environmental and health concern due to its toxicity.
Accurate arsenic determination is crucial in water, soil, agricultural, and food safety.

Purpose of the Study:

To review recent developments in arsenic biosensor technology.
To discuss biosensors utilizing recombinant whole cells, arsenic-binding oligonucleotides, and proteins.
To explore emerging technologies like surface plasmon resonance (SPR) and aptamer-based biosensors for arsenic detection.

Main Methods:

Review of scientific literature on arsenic biosensor development.
Analysis of biosensor designs based on biological recognition elements (cells, DNA, proteins).
Discussion of advanced detection principles including SPR and aptamer functionalities.

Main Results:

Various arsenic biosensor platforms have been developed, offering different advantages.
Recombinant cell-based biosensors provide sensitive detection.
Oligonucleotide and protein-based biosensors offer specificity and potential for miniaturization.
SPR and aptamer technologies show promise for enhanced arsenic sensing capabilities.

Conclusions:

Arsenic biosensors are evolving with diverse biological recognition strategies.
Futuristic approaches like aptamer technology and SPR are expanding the potential of arsenic detection.
Continued research is essential to optimize biosensor performance for real-world arsenic monitoring applications.