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Updated: Apr 25, 2026
Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
Published on: September 20, 2024
Customized photorefractive keratectomy to correct high ametropia after penetrating keratoplasty: A pilot study
Giuseppe De Rosa1, Rosa Boccia1, Carmine Santamaria2
1Multidisciplinary Department of Medical, Surgical and Dental Specialties, Seconda Università di Napoli, Napoli, Italy.
Purpose:
To evaluate preliminarily the safety and efficacy of customized photorefractive keratectomy (PRK) to correct ametropia and irregular astigmatism after penetrating keratoplasty (PK).
Methods:
This pilot study included five eyes of five patients with a mean spherical equivalent of -5.1±1.46D (range from -2.75 to -6.50D). In all cases, ametropia and irregular astigmatism was corrected with topography-guided customized PRK. Ocular examinations with topographic analysis were performed preoperatively as well as at 1, 3 and 6 months after surgery.
Results:
All eyes gained postoperatively at least three Snellen lines of uncorrected visual acuity. Mean refractive spherical equivalent was 0.62±0.63D (range from -0.25 to -1.75D) at 6 months postoperatively.
Conclusion:
Our pilot study suggests that customized PRK can be a safe and effective method for treating ametropia and irregular astigmatisms after PK. Future studies with larger samples and longer follow-ups should be performed to confirm these results.
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