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Defocus Incorporated Multiple Segments (DIMS) spectacle lenses versus 0.01% atropine for myopia control: Two-year
Emilia Wnękowicz-Augustyn1, Edward Wylęgała1, Martyna Kobielnik2
1Chair and Clinical Department of Ophthalmology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Poniatowskiego 15, 40-055 Katowice, Poland.
Purpose:
The global increase in childhood myopia underscores the need for effective control strategies. This study evaluated the effectiveness of Defocus Incorporated Multiple Segments (DIMS) spectacle lenses versus 0.01% atropine eye drops in slowing myopia progression in European children over two years.
Methods:
A total of 110 Polish and Ukrainian children aged 6-16 years without significant ocular pathology were randomised to single-vision spectacles plus nightly 0.01% atropine (group A) or DIMS lenses plus nightly placebo (group B). Primary outcomes were changes in cycloplegic spherical equivalent refraction (SER) and axial length, assessed at 6-month intervals.
Results:
At 24 months, mean axial elongation was lower in group B (0.22 ± 0.22 mm) than in group A (0.32 ± 0.29 mm), particularly among children aged 6-11 years (0.30 ± 0.23 mm vs 0.48 ± 0.31 mm). Similar patterns were observed for SER progression: 0.47 ± 0.47 D in group B versus 0.70 ± 0.58 D in group A, with the greatest difference in younger children (0.59 ± 0.48 D vs 1.05 ± 0.64 D). Differences in older children were smaller.
Conclusions:
In this study, DIMS lenses were associated with greater efficacy than 0.01% atropine in reducing myopia progression, particularly in children aged 6-11 years. Differences in adherence between the interventions should be considered when interpreting these findings. DIMS lenses may represent an effective option for myopia control in European populations.