High-dose immunoglobulin for juvenile myasthenia gravis

A four-year-old girl with the ocular type of myasthenia gravis was effectively treated with intravenous high dose human immunoglobulin. Since conventional anti-choline-esterase drugs failed to induce a satisfactory outcome and the patient continued to suffer from amblyopia, high-dose immunoglobulin was tried according to the method of Gados. Subsequently, she became asymptomatic and her anti-acetylcholine-receptor antibody titer decreased gradually to normal. Currently, she is six years old and continues to be free from complaints and on no medication.