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Updated: Apr 25, 2026
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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
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Left atrial appendage closure using the Amulet device: an initial experience with the second generation amplatzer
Simon Cheung Chi Lam1, Stefan Bertog, Sameer Gafoor
1CardioVascular Center Frankfurt, Seckbacher Landstrasse 65, Frankfurt, Germany.
Summary
The Amulet device offers a feasible and safe option for left atrial appendage closure in patients with atrial fibrillation, demonstrating high success and good short-term outcomes.
Area of Science:
- Cardiology
- Medical Devices
- Interventional Cardiology
Background:
- The Amulet device is a next-generation left atrial appendage (LAA) closure device.
- It is designed to improve upon the Amplatzer Cardiac Plug (ACP) with enhanced implantation and reduced complications.
Purpose of the Study:
- To evaluate the feasibility, safety, and short-term outcomes of LAA closure using the Amulet device.
- Assess the procedural success and complication rates associated with the Amulet device.
Main Methods:
- Implantation of the Amulet device in 17 patients with nonvalvular atrial fibrillation.
- Data collection included baseline, procedural, discharge, and 30/90-day follow-up.
Main Results:
- Successful device implantation in all patients, with sizes ranging from 20-31 mm.
- One procedure-related pericardial effusion managed conservatively; no device embolization.
- At 90 days, no deaths, strokes, or major bleeding; no device-related thrombus or effusion on TEE.
Conclusions:
- The Amulet device is a feasible LAA closure option with novel features.
- Initial experience shows a high success rate and favorable short-term outcomes for Amulet implantation.
