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Pachychoroid neovasculopathy.

Claudine E Pang1, K Bailey Freund

  • 1*Vitreous, Retina, Macula Consultants of New York, New York, New York; †LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear and Throat Hospital, New York, New York; and ‡Department of Ophthalmology, New York University School of Medicine, New York, New York.

Retina (Philadelphia, Pa.)
|August 28, 2014
PubMed
Summary
This summary is machine-generated.

Pachychoroid neovasculopathy, a form of Type 1 neovascularization, is linked to increased choroidal thickness and dilated vessels. This condition may progress to polypoidal choroidal vasculopathy.

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Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Choroidal Neovascularization

Background:

  • Pachychoroid neovasculopathy is characterized by Type 1 neovascularization.
  • It is associated with increased choroidal thickness and dilated choroidal vessels.

Observation:

  • Three cases of pachychoroid neovasculopathy were analyzed retrospectively.
  • Multimodal imaging, including OCT and angiography, was used to assess the patients.

Findings:

  • All patients exhibited Type 1 neovascularization over thickened choroids with dilated vessels.
  • Indocyanine green angiography revealed choroidal hyperpermeability and large choroidal veins.
  • No signs of central serous chorioretinopathy or age-related macular degeneration were present.
  • Polypoidal structures were observed within the neovascular tissue in all cases.

Implications:

  • Pachychoroid neovasculopathy is part of a spectrum of diseases including pachychoroid pigment epitheliopathy and polypoidal choroidal vasculopathy.
  • It should be considered in cases of Type 1 neovascularization with choroidal thickening, especially when AMD is absent.
  • This condition can manifest focally and may progress to polypoidal choroidal vasculopathy.