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Related Concept Videos

Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
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Pigmentation01:19

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
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Related Experiment Video

Updated: Apr 25, 2026

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation
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Hyperpigmentation therapy: a review.

Seemal R Desai1

  • 1Clinical Assistant Professor in the Department of Dermatology at the University of Texas Southwestern Medical Center and is the President & Medical of Innnovative Dermatology, PA in Dallas, Texas. He has served in numerous leadership roles within the American Academy of Dermatology, American Medical Association, Texas Dermatological Society, and Skin of Color Society.

The Journal of Clinical and Aesthetic Dermatology
|August 28, 2014
PubMed
Summary
This summary is machine-generated.

Hyperpigmentation is a common challenge in skin of color patients. This review covers diagnosis, management, and treatment options for this prevalent dermatological condition.

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Area of Science:

  • Dermatology
  • Cutaneous Medicine

Background:

  • Increasing diversity in dermatology clinics highlights the need for specialized care for skin of color patients.
  • Hyperpigmentation is a frequent concern among patients with higher Fitzpatrick skin classifications.
  • Current treatments for hyperpigmentation face challenges due to patient/physician factors and psychosocial considerations.

Purpose of the Study:

  • To review diagnostic dilemmas and cutting-edge treatments for cutaneous anomalies in skin of color.
  • To address the challenges in managing hyperpigmentation in patients with skin of color.
  • To provide insights into the latest clinical research for hyperpigmentation.

Main Methods:

  • Literature review of diagnostic and management strategies for hyperpigmentation in skin of color.
  • Analysis of treatment options, including physician and patient factors.
  • Exploration of contributing factors and psychosocial aspects of hyperpigmentation.

Main Results:

  • Hyperpigmentation remains a significant clinical challenge despite available treatments.
  • Barriers to effective management include reluctance to use certain treatments and failure to identify triggers.
  • Psychosocial impacts of hyperpigmentation require greater clinical attention.

Conclusions:

  • Effective management of hyperpigmentation in skin of color requires a comprehensive approach.
  • Addressing patient/physician factors and psychosocial aspects is crucial for successful treatment outcomes.
  • Further research is needed to optimize diagnostic and therapeutic strategies for hyperpigmentation in diverse populations.