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LSO background radiation as a transmission source using time of flight
Harold Rothfuss1, Vladimir Panin, Andrew Moor
1Siemens Molecular Imaging, 810 Innovation Dr, Knoxville, TN 37932, USA.
Physics in Medicine and Biology
|August 29, 2014
Summary
Lutetium-176 (Lu-176) in LSO scintillators enables simultaneous PET emission and transmission imaging. This background radiation provides data for attenuation and scatter corrections, improving image quality.
Area of Science:
- Nuclear Physics
- Medical Imaging
- Materials Science
Background:
- LSO scintillators (Lu2Sio5:Ce) exhibit background radiation from naturally occurring Lu-176.
- Lu-176 decay involves beta emission coincident with gamma emissions (307, 202, 88 keV).
- This coincidence allows differentiation between positron annihilation events and Lu-176 background data.
Purpose of the Study:
- To investigate the use of Lu-176 background radiation for simultaneous transmission imaging in PET scanners.
- To assess the feasibility of using Lu-176 decay for attenuation and scatter correction data acquisition.
- To determine the required acquisition time for generating useful transmission images.
Main Methods:
- Utilizing time-of-flight and chord length information from coincident Lu-176 beta and gamma emissions.
- Establishing a secondary time window to capture transmission events concurrently with emission data.
- Acquiring continuous blank scans during PET scanner idle times to reconstruct transmission images.
- Reconstructing transmission images using blank scans and measured transmission data.
Main Results:
- Lu-176 background radiation flux is sufficient for reconstructing useful transmission images.
- A 10-minute acquisition time is adequate for generating usable transmission data.
- Simultaneous acquisition of emission and transmission data is achievable.
- Reconstructed transmission images can be applied for attenuation and scatter corrections.
Conclusions:
- Lu-176 background radiation in LSO scintillators can be leveraged for simultaneous PET transmission imaging.
- This method offers a novel approach for obtaining attenuation and scatter correction data without external sources.
- The technique holds potential for enhancing PET image accuracy and enabling simultaneous emission-attenuation estimation.
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