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Transcutaneous PCO2 monitoring in infants hospitalized with viral bronchiolitis

S Gal1, A Riskin, I Chistyakov

  • 1Department of Pediatrics, Bnai Zion Medical Center, The B&R Rappaport Faculty of Medicine, Technion, 47 Golomb Street, Haifa, 31048, Israel, shoshiher@yahoo.com.

European Journal of Pediatrics
|August 29, 2014
PubMed

Insights

Transcutaneous carbon dioxide (PtcCO2) monitoring is feasible in infants with bronchiolitis, showing good correlation with venous (PvCO2). PtcCO2 can serve as a complementary tool for continuous CO2 assessment.

Area of Science:

  • Pediatric Pulmonology
  • Medical Monitoring Technology
  • Respiratory Physiology

Background:

  • Bronchiolitis is a common respiratory infection in infants.
  • Accurate monitoring of carbon dioxide levels is crucial for managing respiratory distress.
  • Current methods for CO2 monitoring can be invasive.

Purpose of the Study:

  • To assess the feasibility of transcutaneous carbon dioxide (PtcCO2) monitoring.
  • To evaluate the correlation and agreement between PtcCO2 and venous carbon dioxide (PvCO2) in infants with bronchiolitis.
  • To determine if PtcCO2 can be a reliable non-invasive tool in the emergency room (ER) and pediatric department.

Main Methods:

  • A feasibility study involving 60 infants diagnosed with bronchiolitis.
  • Prospective collection of simultaneous PtcCO2 measurements (SenTec Digital Monitoring System) and venous blood gas (PvCO2) samples.
  • Analysis of 100 paired measurements to assess correlation and agreement.

Main Results:

  • Good correlation (r=0.71, p<0.001) and adequate agreement between PtcCO2 and PvCO2.
  • Average PtcCO2 was slightly lower than PvCO2 (mean difference ± SD: 1.9 ± 7.0 mmHg).
  • Consecutive changes in PtcCO2 and PvCO2 correlated (r=0.41, p<0.01), and PtcCO2 correlated with disease severity.

Conclusions:

  • Transcutaneous carbon dioxide (PtcCO2) monitoring is feasible in infants with bronchiolitis in ER and pediatric settings.
  • PtcCO2 shows good correlation and adequate agreement with PvCO2, supporting its use as a complementary tool.
  • While not a replacement for blood gas analysis, PtcCO2 offers valuable real-time trending and continuous assessment of CO2 levels.
Abstract

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