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Updated: Apr 25, 2026
10:26
A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
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[Correlation analysis on plasma D-dimer level with deep venous thrombosis after spinal surgery].
Summary
Elevated plasma D-dimer levels (≥500 microg/L) after spinal surgery indicate a higher risk of deep venous thrombosis (DVT). Monitoring D-dimer can effectively predict DVT occurrence in these patients.
Area of Science:
- Orthopedic Surgery
- Vascular Medicine
- Diagnostic Biomarkers
Background:
- Deep venous thrombosis (DVT) is a significant complication following spinal surgery.
- Early detection and risk stratification for DVT are crucial for patient management.
Purpose of the Study:
- To investigate the correlation between plasma D-dimer levels and the incidence of deep venous thrombosis (DVT) in patients undergoing spinal surgery.
- To determine if elevated D-dimer levels can serve as a predictive marker for postoperative DVT.
Main Methods:
- Retrospective analysis of clinical data from 63 patients who underwent spinal surgery.
- Patients were categorized into D-dimer positive (≥500 microg/L) and D-dimer negative (<500 microg/L) groups based on postoperative plasma D-dimer levels.
- Plasma D-dimer levels were monitored at multiple time points post-operation.
Main Results:
- No significant differences were observed in demographic or surgical factors between the D-dimer groups.
- Nineteen patients showed elevated or increasing D-dimer levels post-operation.
- Two cases of DVT occurred in the D-dimer positive group, while no DVTs were detected in the D-dimer negative group.
Conclusions:
- Postoperative plasma D-dimer assay is an effective tool for predicting deep venous thrombosis (DVT) after spinal surgery.
- A D-dimer level of 500 microg/L or higher is identified as a risk factor for DVT development in this patient population.
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