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Updated: Apr 25, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
Published on: November 4, 2015
Chronic thromboembolic pulmonary hypertension.
B E Schölzel1, R J Snijder, J J Mager
1Department of Cardiology, Amphia Hospital, Molengracht 21, 4818, CK, Breda, the Netherlands.
Chronic pulmonary thromboembolic disease causes severe pulmonary hypertension and is fatal if untreated. Pulmonary endarterectomy offers a successful treatment, but careful patient selection is crucial due to comorbidities and disease extent.
Area of Science:
- Cardiology
- Pulmonology
- Vascular Surgery
Background:
- Chronic pulmonary thromboembolic disease (CPTE) is a significant cause of pulmonary hypertension (PH).
- CPTE leads to substantial morbidity and mortality, closely linked to right ventricular dysfunction.
- Untreated CPTE carries a poor prognosis.
Purpose of the Study:
- To review the diagnostic strategies for chronic thromboembolic pulmonary hypertension (CTEPH).
- To outline current surgical and medical therapeutic options for CTEPH.
- To emphasize the importance of expert candidate selection for pulmonary endarterectomy.
Main Methods:
- Review of diagnostic modalities for CTEPH.
- Analysis of outcomes for pulmonary endarterectomy.
- Evaluation of medical management strategies for CTEPH.
Main Results:
- Pulmonary endarterectomy is the primary treatment for CTEPH, demonstrating high success rates.
- Medical therapies and surgical advancements offer options for many patients.
- A subset of patients is ineligible for surgery due to distal disease or comorbidities.
Conclusions:
- Early diagnosis and appropriate management are vital for improving CTEPH outcomes.
- Pulmonary endarterectomy remains the treatment of choice for eligible patients.
- Multidisciplinary expert centers are essential for optimal CTEPH patient management.
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