Modeling nanoscale inhomogeneities for quantitative HAADF STEM imaging
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Updated: Apr 25, 2026

Preparation and Observation of Thick Biological Samples by Scanning Transmission Electron Tomography
Published on: March 12, 2017
Richard Aveyard1, Riccardo Ferrando2, Roy L Johnston3
1Department of Physics, University of York, Heslington, York YO10 5DD, United Kingdom.
Abstract:
High-angle annular dark-field scanning transmission electron microscopy in conjunction with image simulation is an important tool to determine the structure of nanomaterials. We show that molecular dynamics calculations can be combined with multislice image simulations to account for the large effects of surface-enhanced thermal vibrations and structural relaxation on image intensities. Application to a catalytically important gold cluster shows that the image intensity is sensitive to these surface dominated effects with important implications for three-dimensional structural characterizations.
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