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Updated: Apr 25, 2026

Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
Published on: August 11, 2023
Indocyanine green videoangiography methodological variations: review.
Juan A Simal-Julián1, Pablo Miranda-Lloret, Rocio Evangelista-Zamora
1Neurosurgical Department, HUyP La Fe de Valencia, Blv Sur, S/N, Valencia, Spain, juanantonio.simal@gmail.com.
This review explores variations in Indocyanine green videoangiography (ICGVA) for neurovascular pathologies. New techniques offer improved visualization beyond conventional methods, but more research is needed.
Area of Science:
- Neurosurgery
- Vascular Surgery
- Medical Imaging
Background:
- Indocyanine green videoangiography (ICGVA) is a common microsurgical tool for neurovascular conditions.
- Conventional ICGVA has limitations, including the need for exposed vasculature and additive filling patterns.
Purpose of the Study:
- To review and assess methodological variations of ICGVA in neurovascular pathology.
- To identify advancements and compare them to conventional ICGVA techniques.
Main Methods:
- Systematic review of 18 English-language studies on ICGVA in neurovascular pathology.
- Identification and analysis of four primary methodological variants of conventional ICGVA.
Main Results:
- Four variants identified: transient occlusion, intra-arterial catheter administration, endoscopic ICG collection, and quantitative fluorescence analysis.
- These variants aim to overcome conventional ICGVA limitations, offering potentially superior intraoperative information.
Conclusions:
- Methodological variations in ICGVA show promise for enhancing neurovascular surgery.
- Further comparative studies with larger patient cohorts are necessary to validate these advanced techniques against the gold standard.
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