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Updated: Apr 25, 2026

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Signaling pathways in induced naïve pluripotency.

Shoudong Ye1, Dahai Liu2, Qi-Long Ying3

  • 1Center for Stem Cell and Translational Medicine, School of Life Sciences, Anhui University, Hefei 230601, PR China; Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

Current Opinion in Genetics & Development
|September 1, 2014
PubMed
Summary

Naïve pluripotent stem cells from mice and rats can form germline-competent chimeras. Understanding the signaling pathways that maintain this state is key to generating similar stem cells from humans and related species.

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