Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Blood group Du].

M Hrubisko, D Cupaníková, L Ceizelová

    Vnitrni Lekarstvi
    |December 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Sensitive blood group D testing is crucial for accurate Du detection. True Du is rare, weakly immunogenic, and its clinical significance remains uncertain for transfusion recipients and neonates.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Changes in the photosynthetic response of lettuce exposed to toxic element multicontamination under hydroponic conditions.

    Photosynthetica·2024
    Same author

    Rhinitis associated with asthma is distinct from rhinitis alone: The ARIA-MeDALL hypothesis.

    Allergy·2023
    Same author

    Cardiovascular complications among hematopoietic cell transplantation survivors - the role of cardiomarkers.

    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti·2022
    Same author

    Metabolic syndrome in long-term survivors after allogeneic hematopoietic stem cell transplantation.

    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti·2022
    Same author

    Humoral immune responses against facultative pathogen Candida utilis in atopic patients with vulvovaginal candidiasis. Candida utilis glucomannan - New serologic biomarker.

    Immunobiology·2021
    Same author

    Autologous hematopoietic stem cell transplantation for acute myeloid leukemia - single center experience.

    Neoplasma·2017

    Area of Science:

    • Hematology
    • Immunology
    • Transfusion Medicine

    Context:

    • Accurate blood group D typing is essential for transfusion safety.
    • The Du variant presents challenges in serological differentiation from D-positive blood.
    • Understanding the immunogenicity and clinical relevance of Du is critical.

    Purpose:

    • To evaluate the incidence and clinical significance of the true Du blood group variant.
    • To assess the necessity and practical value of Du testing in various clinical scenarios.
    • To provide insights into managing Du-positive blood in transfusion medicine.

    Summary:

    • Sensitive methods are required to distinguish true Du from false positives.
    • The incidence of true Du is low (1-2 per mille) when using precise techniques.

    Related Experiment Videos

  • Du-positive erythrocytes exhibit low immunogenicity and clinical impact, questioning the routine examination's value.

    • Impact:

    • Findings suggest that the clinical significance of true Du is questionable.
    • The study raises doubts about the practical utility of routine Du testing.
    • Recommendations are provided for managing Du in blood donors, recipients, pregnant women, and neonates.