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Related Experiment Video

Updated: Apr 25, 2026

Cell-based Therapy for Heart Failure in Rat: Double Thoracotomy for Myocardial Infarction and Epicardial Implantation of Cells and Biomatrix

Cell-based Therapy for Heart Failure in Rat: Double Thoracotomy for Myocardial Infarction and Epicardial Implantation of Cells and Biomatrix

Published on: September 22, 2014

Multimodality treatment for cardiac angiosarcoma.

Meng Wang¹, Ganglan Fu, Huiqi Jiang

¹Department of Cardiac Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China.

Internal Medicine (Tokyo, Japan)

|September 2, 2014

Summary

This summary is machine-generated.

Multimodality treatment, including chemotherapy, radiotherapy, and targeted therapy, offers hope for improving survival in patients with primary cardiac angiosarcoma, a rare and aggressive cancer. This approach demonstrated a 33-month survival in a case study.

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Cell-based Therapy for Heart Failure in Rat: Double Thoracotomy for Myocardial Infarction and Epicardial Implantation of Cells and Biomatrix

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Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model

Published on: January 21, 2018

Area of Science:

Cardiovascular Pathology
Surgical Oncology
Medical Oncology

Background:

Primary cardiac angiosarcoma is a rare, highly malignant tumor with controversial adjuvant treatment strategies.
Complete surgical excision is the primary treatment, but its efficacy in improving survival is debated.

Observation:

A case of a 30-year-old male with right atrial angiosarcoma is presented.
The patient underwent two surgical resections and received chemotherapy, radiotherapy, and molecular targeted therapy for metastatic disease involving an intestinal segment.

Findings:

The patient achieved a survival of 33 months with multimodality treatment.
A review of existing literature, primarily case reports, on adjuvant therapy for cardiac angiosarcoma was conducted.

Implications:

Limited evidence suggests that multimodality treatment may improve survival outcomes for cardiac angiosarcoma patients.
Further research and larger studies are needed to establish definitive adjuvant treatment protocols for this rare malignancy.