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Gastric xanthelasma.

Y S Chen, J B Lin, K S Dai

    Chinese Medical Journal
    |August 1, 1989
    PubMed
    Summary
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    Gastric xanthelasmas, yellow plaques in the stomach lining, were found in 0.8% of patients. Chronic gastritis may be a contributing factor to their development.

    Area of Science:

    • Gastroenterology
    • Pathology

    Background:

    • Gastric xanthelasmas present as distinct yellow plaques in the stomach.
    • Microscopically, they are characterized by foamy macrophages.

    Purpose of the Study:

    • To determine the prevalence and characteristics of gastric xanthelasmas.
    • To investigate potential associated conditions and etiological factors.

    Main Methods:

    • Retrospective analysis of upper gastrointestinal panendoscopic examinations.
    • Inclusion of 3870 patients.

    Main Results:

    • A prevalence of 0.8% (30 patients) for gastric xanthelasmas was observed.
    • Lesions were more common in males (M:F = 3.3:1), aged 40-60 years.
    • Most lesions were small (2-3 mm), located in the antrum, often along the lesser curvature.

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  • Associated chronic gastritis was noted in all cases, and intestinal metaplasia in 13.3%.

    • Conclusions:

    • Gastric xanthelasmas are uncommon findings during upper endoscopy.
    • Chronic gastritis is a potential etiological factor, though the exact cause remains unknown.