Related Experiment Video
Updated: Apr 24, 2026

Syntheses, Crystallization, and Spectroscopic Characterization of 3,5-Lutidine N-Oxide Dehydrate
Published on: April 24, 2018
Green approach towards the determination of hydroxyzine dihydrochloride in pure and pharmaceutical dosage forms
Amina Mumtaz1, Shahid Hussain2, Muhammad Yasir2
1Applied Chemistry Research Centre, Pakistan Council of Scientific and Industrial Research, Laboratories Complex, Lahore, Pakistan.
Abstract:
A simple eco-friendly method has been developed for detection of hydroxyzine dihydrochloride in pure and pharmaceutical dosage forms. Both conventional system and microwave assisted procedures are used for the development of color. The blue coloured complex is measured spectrophotometrically at 750nm. Peak shift in FT-IR spectra also indicated the formation of complex. The reaction obeys Beer's law over the concentration range of 50- 250βg/mL of hydroxyzine dihydrochloride. The precision value (intra-day and inter-day RSD) for the drug is not greater than 0.79% and recoveries were found to be in range of 99.01-99.99%. The designed method is applicable for periodic determination of hydroxyzine dihydrochloride in pure and pharmaceutical dosage forms.
More Related Videos
Related Concept Videos
Clinically Relevant Drug Product Specifications: Methods of Establishment
Drug Dissolution: Requirements and Profile Comparison
Dosage Interval and Administration Route: Determination Methods
Factors Influencing Drug Absorption: Pharmaceutical Parameters
Dose Size and Dosing Frequency: Determination Methods
Pharmaceutical Alternatives: Polymorphic Form-Related and Particle Size-Related Therapeutic Nonequivalence
![Radiosynthesis of 1-2-[18F]Fluoroethyl-L-Tryptophan using a One-pot, Two-step Protocol](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F63025.jpg&w=3840&q=50)
