Related Experiment Video
Updated: Apr 24, 2026

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
Aggressive giant cell tumour of talus with pulmonary metastasis-a rare presentation
B Udaya Kumar1, P Ravi Sharma2, G Santhosh Ram2
1Professor and HOD, Department of Orthopaedics, King George Hospital, Andhra Medical College , Visakhapatnam, Andhra Pradesh, India .
Abstract:
Giant cell tumour (GCT) is a primary benign neoplasm of bone. It is classically described as a locally invasive tumour that occurs close to the joint of a mature bone. It accounts for 5% of all skeletal tumours. It usually originates from long bones. Giant Cell Tumour of the small bones of the hand and foot are relatively uncommon. Giant Cell Tumour of talus is a rare occurrence. We report a rare presentation of giant cell tumour of the talus in a 62-year-old farmer treated by talectomy and tibiocalcaneal fusion, who later presented with features suggestive of recurrence and secondaries in chest within six months following surgical resection of the primary. Below knee amputation was performed to manage the recurrence. At two years follow-up the patient showed no further progression of pulmonary metastasis or local recurrence.
More Related Videos
08:47Improved Visualization of Lung Metastases at Single Cell Resolution in Mice by Combined In-situ Perfusion of Lung Tissue and X-Gal Staining of lacZ-Tagged Tumor Cells
Published on: August 21, 2012
07:44Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
Published on: March 12, 2018
Related Concept Videos
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...