Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

3.9K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.9K
Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

569
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
569
Transcytosis of IgG01:15

Transcytosis of IgG

3.4K
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
3.4K
Proliferative Phase01:20

Proliferative Phase

1.9K
The proliferative phase typically occurs after menstruation and lasts between 6 to 13 days in a standard 28-day cycle. This phase involves the reconstruction of the endometrium, guided by estrogen produced by the developing ovarian follicle.
Notably, the stratum basale, the basal layer of the endometrium, including the basal parts of the uterine glands, remains unaffected by menstruation. Stem cells in this layer undergo mitosis, regenerating the stratum functionalis and thickening the...
1.9K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

4.8K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessing the association of type 2 diabetes with skin health status: a study of the Northern Finland Birth Cohort 1966.

BMJ open·2026
Same author

Sex-Specific Differences in Perinatal Risk Factors for Atopic Dermatitis: A Large Retrospective Population-Based Cohort Study.

Acta paediatrica (Oslo, Norway : 1992)·2026
Same author

Clinical description and management of two terbinafine-resistant cases of tinea caused by <i>Trichophyton indotineae</i> from Finland.

Skin health and disease·2026
Same author

Prurigo nodularis in children in Finland from 1995 to 2024: a nationwide registry study.

The British journal of dermatology·2026
Same author

The 2025 WAO Guidelines for the classification, diagnosis, and treatment of hereditary angioedema, with consideration of worldwide disparities.

The World Allergy Organization journal·2026
Same author

Body Image Satisfaction among Patients with Female Acne.

Acta dermato-venereologica·2026

Related Experiment Video

Updated: Apr 24, 2026

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
05:05

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid

Published on: June 17, 2025

1.6K

Gestational pemphigoid.

Laura Huilaja1, Kaarin Mäkikallio, Kaisa Tasanen

  • 1Department of Dermatology, Medical Research Center, University of Oulu, Oulu University Hospital, Oulu, Finland. laura.huilaja@oulu.fi.

Orphanet Journal of Rare Diseases
|September 3, 2014
PubMed
Summary

Gestational pemphigoid (PG) is a rare pregnancy-related autoimmune skin disease. Prompt diagnosis and management, involving dermatologists and obstetricians, are crucial for maternal and fetal health.

Area of Science:

  • Dermatology
  • Immunology
  • Obstetrics

Background:

  • Gestational pemphigoid (PG) is a rare autoimmune blistering skin disease unique to pregnancy.
  • It is characterized by autoantibodies targeting placental BP180 (collagen XVII), leading to skin basement membrane damage.

Purpose of the Study:

  • To summarize the key aspects of gestational pemphigoid, including its pathogenesis, diagnosis, management, and implications for pregnancy.
  • To highlight the importance of multidisciplinary care and patient education.

Main Methods:

  • Diagnosis confirmed by immunofluorescence analysis of skin biopsy.
  • Serum levels of pemphigoid antigen BP180 antibody used to monitor disease activity.

Main Results:

More Related Videos

Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

9.9K
Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues
11:54

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues

Published on: October 20, 2019

8.3K

Related Experiment Videos

Last Updated: Apr 24, 2026

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
05:05

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid

Published on: June 17, 2025

1.6K
Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

9.9K
Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues
11:54

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues

Published on: October 20, 2019

8.3K
  • Mild PG treated with topical corticosteroids; severe cases managed with oral corticosteroids.
  • PG often exacerbates around delivery but typically resolves postpartum.
  • Subsequent pregnancies carry a risk of relapse.

    • Conclusions:

    • Gestational pemphigoid necessitates collaborative management between dermatologists and obstetricians due to associated risks like prematurity and fetal growth restriction.
    • Patients require counseling regarding disease recurrence in future pregnancies and with hormonal contraception.