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Published on: February 29, 2020
Fungal otitis externa as a cause of tympanic membrane perforation: a case series
James Eingun Song1, Thomas J Haberkamp, Riddhi Patel
1Department of Dermatology, University of California, Irvine, 118 Med Surge I, Irvine, CA 92697, USA. Esong812@gmail.com.
Abstract:
We describe a series of 11 patients--8 men and 3 women, aged 18 to 70 years (mean: 46.0)--who had fungal otitis externa that had been complicated by a tympanic membrane perforation. These patients had been referred to us for evaluation of chronic, mostly treatment-refractory otitis externa, which had manifested as otorrhea, otalgia, and/or pruritus. Seven of the 11 patients had no history of ear problems prior to their current condition. Five patients had been referred to us by a primary care physician and 4 by an otolaryngologist; the other 2 patients were self-referred. All patients were treated with a thorough debridement of the ear and one of two antifungal medication regimens. Eight of the 11 patients experienced a complete resolution of signs and symptoms, including closure of the tympanic membrane perforation. The other 3 patients underwent either a tympanoplasty (n = 2) or a fat-graft myringotomy (n = 1) because the perforation did not close within a reasonable amount of time. This series demonstrates that the nonspecific signs and symptoms of fungal otitis externa can make diagnosis difficult for both primary care physicians and general otolaryngologists. This study also demonstrates that most cases of tympanic membrane perforation secondary to fungal otitis externa will resolve with cleaning of the ear and proper medical treatment. Therefore, most patients with this condition will not require surgery.
Insights
Fungal otitis externa with tympanic membrane perforation often presents with vague symptoms, complicating diagnosis. However, thorough ear cleaning and antifungal treatment effectively resolve most cases, often healing the perforation without surgery.
Area of Science:
- Otolaryngology
- Mycology
- Infectious Diseases
Background:
- Fungal otitis externa (FOE) can present with nonspecific symptoms, leading to diagnostic challenges.
- Complicated FOE involving tympanic membrane perforation (TMP) requires specific management strategies.
- Chronic, treatment-refractory ear conditions may indicate underlying FOE with TMP.
Purpose of the Study:
- To evaluate the clinical presentation and treatment outcomes of fungal otitis externa complicated by tympanic membrane perforation.
- To assess the efficacy of conservative management including debridement and antifungal therapy for FOE with TMP.
- To determine the necessity of surgical intervention for TMP secondary to fungal infections.
Main Methods:
- Retrospective case series of 11 patients with fungal otitis externa and TMP.
- Patients received thorough ear debridement and one of two antifungal medication regimens.
- Outcomes including symptom resolution and TMP closure were documented.
Main Results:
- Eight out of 11 patients achieved complete resolution of symptoms and TMP closure.
- Three patients required surgical intervention (tympanoplasty or fat-graft myringotomy) for persistent perforation.
- Diagnosis of FOE was challenging for referring physicians due to nonspecific symptoms.
Conclusions:
- Fungal otitis externa with tympanic membrane perforation can be effectively treated with conservative measures like debridement and antifungal therapy.
- Most tympanic membrane perforations secondary to fungal otitis externa resolve with medical management, minimizing the need for surgery.
- Increased physician awareness is needed to diagnose fungal otitis externa presenting with chronic, refractory symptoms.
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