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Antimicrobial activity of some essential oils against oral multidrug-resistant Enterococcus faecalis in both
Fethi Benbelaïd1, Abdelmounaïm Khadir1, Mohamed Amine Abdoune1
1Laboratory of Applied Microbiology in Food, Biomedical and Environment (LAMAABE), Aboubekr Belkaïd University, PO Box 119, 13000 Tlemcen, Algeria.
Objective:
To evaluate some essential oils in treatment of intractable oral infections, principally caused by biofilm of multidrug-resistant Enterococcus faecalis (E. faecalis), such as persistent endodontic infections in which their treatment exhibits a real challenge for dentists.
Methods:
Ten chemically analyzed essential oils by gas chromatography-mass spectrometry were evaluated for antimicrobial activity against sensitive and resistant clinical strains of E. faecalis in both planktonic and biofilm state using two methods, disk diffusion and broth micro-dilution.
Results:
Studied essential oils showed a good antimicrobial activity and high ability in E. faecalis biofilm eradication, whether for sensitive or multidrug-resistant strains, especially those of Origanum glandulosum and Thymbra capitata with interesting minimum inhibitory concentration, biofilm inhibitory concentration, and biofilm eradication concentration values which doesn't exceed 0.063%, 0.75%, and 1.5%, respectively.
Conclusions:
Findings of this study indicate that essential oils extracted from aromatic plants can be used in treatment of intractable oral infections, especially caused by biofilm of multidrug-resistant E. faecalis.
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