Paroxysmal autonomic instability with dystonia (PAID) syndrome following cardiac arrest
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Updated: Apr 24, 2026

Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia
Published on: September 12, 2020
Dheeraj Kapoor1, Deepak Singla, Jasveer Singh
1Department of Anaesthesia and Intensive Care, Government Medical College and Hospital, Chandigarh, India. kapoor.dheeraj72@gmail.com.
Abstract:
Paroxysmal autonomic instability with dystonia (PAID) appears to be a unique syndrome following brain injury. It can echo many life-threatening conditions, making its early recognition and management a challenge for intensivists. A delay in early recognition and subsequent management may result in increased morbidity, which is preventable in affected patients. Herein, we report the case of a patient who was diagnosed with PAID syndrome following prolonged cardiac arrest, and discuss the pathophysiology, clinical presentation and management of this rare and under-recognised clinical entity.
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