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Sleep quality in patients with Behçet's disease
Levent Yazmalar1, İbrahim Batmaz1, Mustafa A Sarıyıldız1
1Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
Patients with Behçet
Area of Science:
- Rheumatology
- Sleep Medicine
- Psychiatry
Background:
- Behçet's disease (BD) is a multisystemic inflammatory disorder.
- Sleep disturbances are common but understudied in BD patients.
Purpose of the Study:
- To evaluate sleep quality in patients with Behçet's disease.
- To identify variables associated with poor sleep in BD.
Main Methods:
- 112 BD patients and 67 controls completed the Pittsburgh Sleep Quality Index (PSQI).
- Quality of Life (QoL) was assessed using the Nottingham Health Profile (NHP).
- Anxiety and depression were measured by the Hospital Anxiety and Depression Scale (HADS).
Main Results:
- BD patients reported significantly poorer subjective sleep quality, longer sleep latency, and higher overall sleep disturbance (PSQI scores) than controls.
- Poor sleep quality in BD was strongly correlated with anxiety, depression, and impaired QoL.
- Genital ulcers and arthritis were identified as predictors of poor sleep quality in BD patients.
Conclusions:
- Sleep quality is significantly impaired in patients with Behçet's disease.
- Anxiety, depression, reduced QoL, genital ulcers, and arthritis are associated with disturbed sleep in BD.
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