Related Experiment Video
Updated: Apr 24, 2026

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451
Published on: April 18, 2025
Brain PET in the diagnosis of Alzheimer's disease
Charles Marcus1, Esther Mena, Rathan M Subramaniam
1*Post Doctorate Research Fellow in the Russell H. Morgan, Department of Radiology and Radiological Sciences at Johns Hopkins University in Baltimore, MD; †Nuclear Medicine Resident in the Russell H. Morgan, Department ofRadiology and Radiological Sciences at Johns Hopkins University in Baltimore, MD; ‡Associate Professor in the Russell H. Morgan, Department of Radiology and Radiological Sciences, Department of Oncology, Department of Otolaryngology-Head and Neck Surgery at Johns Hopkins School of Medicine, and the Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Objectives:
The aim of this article was to review the current role of brain PET in the diagnosis of Alzheimer dementia. The characteristic patterns of glucose metabolism on brain FDG-PET can help in differentiating Alzheimer's disease from other causes of dementia such as frontotemporal dementia and dementia of Lewy body. Amyloid brain PET may exclude significant amyloid deposition and thus Alzheimer's disease in appropriate clinical setting.
Conclusions:
FDG-PET and amyloid PET imaging are valuable in the assessment of patients with Alzheimer's disease.
More Related Videos
08:27Establishment of a Valuable Mimic of Alzheimer's Disease in Rat Animal Model by Intracerebroventricular Injection of Composited Amyloid Beta Protein
Published on: July 29, 2018
08:25Detecting Amyloid-β Accumulation via Immunofluorescent Staining in a Mouse Model of Alzheimer's Disease
Published on: April 19, 2021
Related Concept Videos
Alzheimer Disease ll: Pathophysiology
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
Alzheimer's Disease: Treatment
Alzheimer Disease l: Introduction
Dementia l: Introduction