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Quality Management of the Immunohistochemistry Laboratory: A Practical Guide

Justin M M Cates1, K Ashley Troutman

  • 1Department of Pathology, Medical Center North C-3321, Vanderbilt University Medical Center, Nashville, TN.

Applied Immunohistochemistry & Molecular Morphology : AIMM
|September 10, 2014
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Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
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