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Updated: Aug 23, 2026

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
Acute myeloid leukemia with unusual mature lymphoid-like morphology in a subset of blasts
Christopher Vossen1, Clarissa E Jordan2
1Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 1st St SW, Rochester, 55905, MN, United States.
Abstract:
We report a case of newly diagnosed acute myeloid leukemia with atypical blast morphology. Peripheral blood smear showed an atypical, dimorphic population of myeloblasts, including a subset with typical morphology and a separate subset with unusual mature lymphoid-like morphology. Flow cytometric immunophenotyping was crucial in characterizing the dimorphic population as a single myeloid blast population.
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