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Updated: Apr 24, 2026
Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats
Published on: March 13, 2012
Behavioral analysis after sciatic nerve compression in albino rats
P Anand1, D C Mathangi2, Jeraud Mathew1
1Department of Physiology, Rajah Muthiah Medical and Dental College, Annamalai University, Annamalai Nagar, Chidambaram, INDIA.
Background:
Walking track analysis which has been widely used to examine the recovery of gait functions in rats with sciatic nerve injury.
Purpose:
The present study was aimed to objectively analyze and quantify the degree of functional recovery in locomotor behavior of rats after inflicting sciatic nerve crush injury.
Methods:
Wistar rats trained on various runways, viz., narrow beam, grid and staircase, were subsequently tested following sciatic nerve crush injury.
Results:
Locomotor ability of injured rats on runways gradually recovered to the level that was not significantly different from their corresponding preoperative level by the sixth postoperative week.
Conclusion:
Conventional run ways can be objectively used for quantification of the level of recovery.
