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Published on: August 21, 2017
Intestinal obstruction caused by extramedullary hematopoiesis and ascites in primary myelofibrosis
Xiu-Qing Wei1, Zong-Heng Zheng1, Yi Jin1
1Xiu-Qing Wei, Jin Tao, Kodjo-Kunale Abassa, Zhuo-Fu Wen, Bin Wu, Department of Gastroenterology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China.
Abstract:
Primary myelofibrosis (PMF) is a clonal hematopoietic stem cell disorder. It is characterized by bone marrow fibrosis, extramedullary hematopoiesis with hepatosplenomegaly and leukoerythroblastosis in the peripheral blood. The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever. Here we report a rare case of PMF with anemia, small bowel obstruction and ascites due to extramedullary hematopoiesis and portal hypertension. The diagnosis was difficult to establish before surgery and the differential diagnosis is discussed.
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