Related Experiment Video
Updated: Apr 24, 2026

Neuropharmacological Manipulation of Restrained and Free-flying Honey Bees, Apis mellifera
Published on: November 26, 2016
Grayanotoxin (mad honey) - ongoing consumption after poisoning
Serkan Emre Eroğlu1, Oğuz Urgan1, Ozge Ecmel Onur1
1Department of Emergency Medicine, Marmara University Pendik Research and Training Hospital, İstanbul, Turkey.
Mad honey poisoning patients in intensive care were significantly less likely to continue consuming toxic honey compared to those with milder symptoms. Educating patients about mad honey hazards is crucial.
Area of Science:
- Toxicology
- Public Health
- Clinical Medicine
Background:
- Certain honey types, known as
- mad honey
- in Turkey, contain Grayanotoxin I, a potent toxin.
- Consumption can lead to severe health issues including bradycardia and hypotension.
Purpose of the Study:
- To analyze patient behaviors regarding mad honey consumption post-diagnosis.
- To compare continued consumption rates between different patient groups.
Main Methods:
- A cross-sectional study involving 38 mad honey poisoning patients.
- Patient data compared at admission and one month post-discharge via phone interviews.
- Chi-square test used to analyze consumption continuation differences.
Main Results:
- 12 of 16 patients discharged from emergency observation continued mad honey consumption.
- 16 of 18 intensive care unit patients discontinued consumption.
- A statistically significant difference in consumption continuation was observed between the groups.
Conclusions:
- Patients consuming mad honey must be thoroughly informed about its associated hazards.
- Clear communication of serious consequences is vital for preventing recurrence.
Related Concept Videos
Prevention of Further Absorption of Poison
Anticholinesterase Agents: Poisoning and Treatment
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
Pharmaceutical Poisoning: Treatment Strategies
Pharmaceutical Poisoning: Potential Scenarios
Toxidromes: Clinical Features
Antidotes
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...

