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Theranostics: A treasured tailor for tomorrow
S Jeelani1, R C Jagat Reddy2, Thangadurai Maheswaran3
1Department of Oral Medicine and Radiology, Indira Gandhi Institute of Dental Sciences, Puducherry, India.
Theranostics combines diagnosis and therapeutics for personalized medicine, ensuring the right drug for the right patient. This approach, utilizing pharmacogenetics and nanomedicine, transitions healthcare to predictive and preventive strategies.
Area of Science:
- Biomedical Sciences
- Pharmacology
- Nanotechnology
Background:
- Theranostics represents a paradigm shift from conventional medicine towards patient-centered, personalized care.
- It integrates diagnostic and therapeutic strategies to optimize treatment efficacy and safety.
- The approach is crucial for advancing precision medicine, tailoring treatments to individual patient profiles.
Purpose of the Study:
- To highlight the principles and significance of theranostics in modern pharmacotherapy.
- To emphasize the role of genetics, proteomics, and biomarker profiling in theranostic applications.
- To explore the application of nanomedicine within theranostics, particularly in oncology.
Main Methods:
- Review of current literature on theranostics and personalized medicine.
- Analysis of the integration of diagnostic tools with therapeutic agents.
- Examination of the role of omics technologies (genomics, proteomics) and nanotechnology in theranostics.
Main Results:
- Theranostics enables targeted, safe, and efficient drug delivery, improving patient outcomes.
- Pharmacogenetics, proteomics, and biomarker profiling are foundational to theranostic strategies.
- Nanomaterials like liposomes, nanoparticles, and quantum dots are vital for advanced theranostic applications, especially in oncology.
Conclusions:
- Theranostics facilitates a transition from "trial and error" medicine to predictive, preventive, and personalized pharmacotherapy.
- It offers a cost-effective and successful treatment protocol tailored to individual patient needs.
- The integration of diagnostics, therapeutics, and advanced technologies like nanomedicine enhances the quality of healthcare.
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