Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

895
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
895
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

392
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
392
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

354
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
354
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

2.9K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
2.9K
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

375
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
375
Sleepwalking and Sleep Talking01:17

Sleepwalking and Sleep Talking

1.7K
Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Homocysteine increases phosphorylation and aggregation of α-synuclein.

Journal of clinical biochemistry and nutrition·2026
Same author

PRDX4 Potentially Serves as an Independent Marker for Early Recurrence of Oral Squamous Cell Carcinoma.

Anticancer research·2026
Same author

Combined assessment of stromal tumor infiltrating lymphocytes and tumor peroxiredoxin 4 expression improved prognostic stratification in postoperative pancreatic cancer patients.

Diagnostic pathology·2026
Same author

Effects of 6-month administration of tofogliflozin on cardiac function in elderly patients with heart failure with preserved ejection fraction: A retrospective study of a patient cohort.

Medicine·2024
Same author

Procalcitonin, brain natriuretic peptide and albumin as markers to predict prognosis in hospitalized older Japanese patients with a risk of infection.

Geriatrics & gerontology international·2024
Same author

Association of Olfactory and Gustatory Function with Memory among Community-Dwelling Independent Older Adults.

Annals of geriatric medicine and research·2024

Related Experiment Video

Updated: Apr 24, 2026

Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

7.3K

Sleep apnea in the elderly.

Masashi Okuro1, Shigeto Morimoto

  • 1Department of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.

Current Opinion in Psychiatry
|September 12, 2014
PubMed
Summary
This summary is machine-generated.

Elderly individuals often develop sleep apnea syndrome (SAS) alongside other health issues. Continuous positive airway pressure treatment can improve SAS symptoms and related conditions like hypertension and cognitive decline.

More Related Videos

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

1.6K
Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

19.7K

Related Experiment Videos

Last Updated: Apr 24, 2026

Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

7.3K
Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

1.6K
Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

19.7K

Area of Science:

  • Gerontology
  • Sleep Medicine
  • Internal Medicine

Background:

  • Sleep apnea syndrome (SAS) in the elderly presents diverse clinical manifestations and numerous complications.
  • SAS is associated with multiple medical departments due to its varied symptoms.

Purpose of the Study:

  • To provide a literature-based overview of sleep apnea syndrome in the elderly population.
  • To outline the clinical presentation, complications, and management of SAS in older adults.

Main Methods:

  • Literature review of studies on sleep apnea syndrome in the elderly.
  • Synthesis of existing research on SAS symptoms, comorbidities, and treatment outcomes.

Main Results:

  • SAS frequently coexists with lifestyle-related diseases including hypertension, hyperlipidemia, diabetes mellitus, and metabolic syndrome.
  • Continuous positive airway pressure (CPAP) treatment can alleviate SAS symptoms and associated conditions.
  • CPAP therapy may also improve depression symptoms and slow cognitive decline in elderly patients with SAS.

Conclusions:

  • Aging-related physiological changes, chronic respiratory disorders, cardiovascular diseases, and strokes contribute to SAS development in the elderly.
  • Further research is needed to establish clear prognostic judgments and new treatment standards for SAS in older adults.