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Updated: Apr 24, 2026
Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
Published on: August 11, 2023
Spectral-domain optical coherence tomography findings in polypoidal choroidal vasculopathy suggest a type 1
Saeed T Alshahrani1, Hanan N Al Shamsi2, Eman S Kahtani2
1King Fahad Specialist Hospital, Dammam, Saudi Arabia ; King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Purpose:
To report spectral-domain optical coherence tomography (SD-OCT) findings in polypoidal choroidal vasculopathy (PCV).
Patients And Methods:
Seventeen eyes of 15 consecutive patients diagnosed with PCV based on typical clinical and angiographic findings were imaged with macular SD-OCT including line scans passing through the polyps.
Results:
SD-OCT findings included typical and atypical retinal pigment epithelial (RPE) detachments and subretinal and intraretinal fluid in all eyes. In the areas corresponding to the polypoidal lesions, well-delineated round-oval, sub-RPE cavities were present and were adherent to the posterior surface of the detached RPE above Bruch membrane. No retinal or choroidal connections to the cavities were noted.
Conclusion:
These SD-OCT findings document that the vascular lesions in PCV are not located in the inner choroid, but in the sub-RPE space, suggesting that PCV is a variant of type 1 choroidal neovascularization rather than a distinct clinical entity as initially thought.
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