Related Experiment Video
Updated: Apr 24, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Effective interventions to improve medication adherence in Type 2 diabetes: a systematic review
Joni L Strom Williams1, Rebekah J Walker2, Brittany L Smalls1
1Center for Health Disparities Research, Medical University of South Carolina, Charleston, SC, USA ; Division of General Internal Medicine & Geriatrics, Department of Medicine, Medical University of South Carolina, Charleston, SC, USA.
Identifying effective medication adherence interventions for Type 2 diabetes is challenging due to study design variability. Future research should focus on tailored strategies for better patient outcomes.
Area of Science:
- Endocrinology
- Pharmacology
- Public Health
Background:
- Medication adherence significantly impacts diabetes management and patient outcomes.
- While various interventions exist to improve adherence, their effectiveness in Type 2 diabetes is not well-defined.
Purpose of the Study:
- To evaluate the effectiveness of interventions aimed at improving medication adherence in adults with Type 2 diabetes.
- To identify gaps and future research directions in this field.
Main Methods:
- A systematic literature search was conducted on Medline for studies published between January 2000 and May 2013.
- Inclusion criteria focused on interventions measuring medication adherence in adult Type 2 diabetes patients.
Main Results:
- Twenty-seven studies met the inclusion criteria.
- Thirteen of these studies reported a statistically significant improvement in medication adherence.
Conclusions:
- Significant heterogeneity in study designs and adherence measures complicates the identification of universally effective interventions.
- Medication adherence alone may not be sufficient for optimal glycemic control; tailored interventions and clear adherence indicators are needed.
Related Concept Videos
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Drug Therapy
Antianxiety Medications
Oral Hypoglycemic Agents: Biguanides and Glitazones
Diabetes Mellitus: Type 2 and Gestational
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...

