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    Area of Science:

    • Public Health
    • Epidemiology
    • Immunization

    Background:

    • Pertussis (whooping cough) is resurging despite childhood immunization requirements.
    • Adults may serve as reservoirs for pertussis, potentially transmitting it to infants.
    • Infants under 2 years are most vulnerable to severe pertussis complications.

    Purpose of the Study:

    • To examine current pertussis incidence in the United States.
    • To investigate adult knowledge regarding pertussis and Tdap vaccination.
    • To identify strategies for reducing pertussis in high-risk infants.

    Main Methods:

    • Review of pertussis incidence data in the US.
    • Assessment of adult caregiver awareness and attitudes towards pertussis and Tdap boosters.
    • Exploration of targeted immunization program feasibility.

    Main Results:

    • Analysis indicates a puzzling resurgence of pertussis.
    • Adult knowledge gaps regarding pertussis transmission and Tdap importance were identified.
    • Worksite-based Tdap immunization programs show potential for increasing adult uptake.

    Conclusions:

    • Adult immunization with the tetanus, diphtheria, and acellular pertussis (Tdap) booster is crucial for preventing infant pertussis.
    • Implementing accessible immunization programs, such as at worksites, can improve adult Tdap coverage.
    • Targeted strategies are needed to protect infants from pertussis, particularly from adult carriers.