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[Radiotherapy indications for non-malignant diseases in 2014].

P Van Houtte1, M Roelandts1, G Kantor2

  • 1Département de radio-oncologie, institut Jules-Bordet, université Libre de Bruxelles, 121, boulevard de Waterloo, Bruxelles 1000, Belgique.

Cancer Radiotherapie : Journal De La Societe Francaise De Radiotherapie Oncologique
|September 14, 2014
PubMed
Summary
This summary is machine-generated.

Radiotherapy for non-malignant conditions is updated, with established uses like preventing heterotopic bone and keloids. Benign disease radiation requires the same rigorous patient information on risks and benefits as malignant treatments.

Keywords:
Affection bénigneNon-malignant diseaseRadiotherapyRadiothérapie

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Area of Science:

  • Oncology
  • Radiotherapy
  • Non-malignant Diseases

Background:

  • The 2005 review of radiotherapy indications for benign conditions serves as a baseline.
  • Significant shifts in established indications have been minimal since the previous review.
  • Certain previously explored applications, like macular degeneration, are no longer current practice.

Purpose of the Study:

  • To provide an updated review of current radiotherapy indications for non-malignant diseases.
  • To highlight the enduring classical indications for radiation therapy in benign conditions.
  • To emphasize the importance of consistent treatment criteria for both benign and malignant diseases.

Main Methods:

  • Literature review and synthesis of evidence regarding radiotherapy for non-malignant conditions.
  • Exclusion of indications treated solely by radiosurgery.
  • Analysis of changes and continuities in treatment guidelines since 2005.

Main Results:

  • Classical indications for radiotherapy in non-malignant diseases, such as prevention of heterotopic bone formation and keloids, remain valid.
  • Indications like macular degeneration treatment and prevention of coronary restenosis are now considered historical.
  • No major changes in the core indications have occurred since the 2005 review.

Conclusions:

  • Radiotherapy for non-malignant diseases continues to rely on established indications like heterotopic ossification and keloid prevention.
  • The therapeutic landscape for benign conditions has seen limited evolution, with some past applications becoming obsolete.
  • Crucially, radiation treatment for benign conditions must adhere to the same stringent ethical and quality standards as for malignant diseases, including comprehensive patient information on risks, benefits, and treatment quality.