Posthumous reproduction with surplus in vitro fertilization embryos: a study exploring users' choices

Area of Science:

• Reproductive Medicine
• Embryology
• Bioethics

Background:

• In vitro fertilization (IVF) generates surplus cryopreserved embryos.
• Posthumous assisted reproduction (PAR) presents complex ethical and psychological considerations.
• Understanding patient consent for embryo utilization is crucial.

Purpose of the Study:

• To analyze IVF users' consent choices for posthumous assisted reproduction (PAR) using surplus cryopreserved embryos.
• To assess the agreement rates for different uses of surplus embryos, including PAR.

Main Methods:

• Content analysis of signed consent forms from 498 individuals at a public IVF clinic.
• Examination of patient agreements for embryo utilization for training, research, and partner reproduction after death.

Main Results:

• 68% consented to embryo use for training/ART improvement; 56% for research.
• 73.5% of men and 61.8% of women agreed to leave cryopreserved embryos to partners for reproductive use after death.
• A majority of individuals agreed to leave embryos for PAR in a real-life consent context.

Conclusions:

• Most individuals agree to posthumous assisted reproduction (PAR) in a practical setting.
• PAR involves significant psychological and ethical challenges for individuals and potential offspring.
• Enhanced counseling is necessary to ensure informed consent for PAR, given its acceptability.