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Multiple left ventricular thrombi in a patient with dilated cardiomyopathy and cerebral infarction: a case report
Takanao Mine1, Ikuo Sato, Hiroji Miyake
1Department of Internal Medicine, Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan. mine@hyo-med.ac.jp.
Insights
Patients with heart failure and reduced left ventricular function may benefit from anticoagulation therapy. This case study highlights the potential advantages of anticoagulation in managing left ventricular thrombi and preventing cerebral infarction.
Area of Science:
- Cardiology
- Neurology
Background:
- Uncertainty exists regarding anticoagulation therapy for patients with sinus rhythm and reduced left ventricular function during or after heart failure treatment.
- Dilated cardiomyopathy can lead to heart failure and increase the risk of thromboembolic events.
Observation:
- A 67-year-old man with heart failure due to dilated cardiomyopathy developed cerebral infarction post-discharge.
- Multiple left ventricular thrombi persisted despite initial treatment.
Findings:
- Edaravone and heparin administration led to complete resolution of paralysis within 2 days.
- A persistent left visual field defect was noted after treatment.
Implications:
- Anticoagulation therapy may be beneficial for patients with sinus rhythm and reduced left ventricular function during heart failure management.
- This case underscores the importance of considering anticoagulation in heart failure patients at risk for thromboembolism.
Introduction:
It is not clear whether patients with sinus rhythm and reduced left ventricular function should be treated with anticoagulation therapy during or after treatment for heart failure.
Case Presentation:
A 67-year-old Japanese man was hospitalized at our institution with heart failure due to dilated cardiomyopathy. On day after discharge, he developed cerebral infarction and showed persistence of multiple left ventricular thrombi. His paralysis completely improved at 2 days after edaravone and heparin administration; however, his left visual field defect persisted.
Conclusion:
Patients in sinus rhythm with reduced left ventricular function might benefit from anticoagulation therapy during treatment for heart failure.
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